产品服务
信号通路
详细信息
推荐稀释比 ： IF 1:50-200;IHC 1:50-300
组成 ： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 ： The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
储存 ： -15°C to -25°C/1 year(Do not lower than -25°C
浓度 ： 1 mg/ml
克隆性 ： Monoclonal
克隆号 ： 7C3
抗原&靶点信息
特异性 ： The antibody detects endogenous NBR1 protein
基因名称 ： NBR1 1A13B KIAA0049 M17S2 MIG19
蛋白名称 ： Next to BRCA1 gene 1 protein (Cell migration-inducing gene 19 protein) (Membrane component chromosome 17 surface marker 2) (Neighbor of BRCA1 gene 1 protein) (Protein 1A1-3B)
别名 ： Next to BRCA1 gene 1 protein;Cell migration-inducing gene 19 protein;Membrane component chromosome 17 surface marker 2;Neighbor of BRCA1 gene 1 protein;Protein 1A1-3B;
背景：
The protein encoded by this gene was originally identified as an ovarian tumor antigen monitored in ovarian cancer. The encoded protein contains a B-box/coiled-coil motif, which is present in many genes with transformation potential. It functions as a specific autophagy receptor for the selective autophagic degradation of peroxisomes by forming intracellular inclusions with ubiquitylated autophagic substrates. This gene is located on a region of chromosome 17q21.1 that is in close proximity to the BRCA1 tumor suppressor gene. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2014],
细胞定位 ： Cytoplasm . Cytoplasmic vesicle, autophagosome . Lysosome . Cytoplasm, myofibril, sarcomere, M line . In cardiac muscles localizes to the sarcomeric M line (By similarity). Is targeted to lysosomes for degradation (PubMed:19250911). .
推荐产品
相关文献
我们始终开放沟通，期待为您提供支持。
我们以一抗、二抗产品为核心，深耕抗体试剂细分领域。依托自主搭建的核心技术平台与专业的研发生产团队，我们为全球高校、科研院所、生物医药企业等客户提供高可靠性的生物试剂产品及全链条技术
支持服务。自成立以来，Pinofibio 始终坚守“以科研需求为导向”的发展理念，通过完善的研发体系、严苛的质量控制与高效的服务响应，致力于构建覆盖多物种、多靶点的抗体产品矩阵，助力科研工作者攻克技术难题，推动生物医药产业的创新发展。
武汉市皮诺飞生物科技有限公司
地址：湖北省武汉市江夏区神墩四路 666 号武汉国英种业大厦A栋14F
邮箱：pinuofei2017@163.com
TEL：15392937510
小红书
实验服务
公众号
抗体服务
微信客服