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SIAH1 rabbit pAb

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说明书下载
货号: PG4564
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
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靶点: SIAH1
应用: WB
反应性 : Human,Rat
宿主物种 : Rabbit
MW(CalcμLated) : 31kD
同种型-Isotype : IgG

隐藏域元素占位

详细信息

推荐稀释比 : WB 1:500-2000
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal

抗原&靶点信息

特异性 : This antibody detects endogenous levels of SIAH1 at Human/Rat
基因名称 : SIAH1 HUMSIAH
蛋白名称 : SIAH1

数据库链接:

Organism

基因 ID

SwissProt

背景:

This gene encodes a protein that is a member of the seven in absentia homolog (SIAH) family. The protein is an E3 ligase and is involved in ubiquitination and proteasome-mediated degradation of specific proteins. The activity of this ubiquitin ligase has been implicated in the development of certain forms of Parkinson's disease, the regulation of the cellular response to hypoxia and induction of apoptosis. Alternative splicing results in several additional transcript variants, some encoding different isoforms and others that have not been fully characterized. [provided by RefSeq, Jul 2008],

细胞定位 : Cytoplasm. Nucleus. Predominantly cytoplasmic. Partially nuclear.

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