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货号: PD6516
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
所属分类：
靶点: Cdc14a phosphatase
应用： WB,ELISA
反应性 ： Human,Mouse
宿主物种 ： Rabbit
MW(Observed)： 66kD
同种型-Isotype ： IgG
隐藏域元素占位
详细信息
推荐稀释比 ： WB 1:500-1:2000;ELISA 1:20000;Not yet tested in other applications.
组成 ： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 ： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 ： -15°C to -25°C/1 year(Do not lower than -25°C
浓度 ： 1 mg/ml
克隆性 ： Polyclonal
抗原&靶点信息
特异性 ： Cdc14a phosphatase Polyclonal Antibody detects endogenous levels of Cdc14a phosphatase protein.
基因名称 ： CDC14A
蛋白名称 ： Dual specificity protein phosphatase CDC14A
别名 ： CDC14A;Dual specificity protein phosphatase CDC14A;CDC14 cell division cycle 14 homolog A
背景：
cell division cycle 14A(CDC14A) Homo sapiens The protein encoded by this gene is a member of the dual specificity protein tyrosine phosphatase family. It is highly similar to Saccharomyces cerevisiae Cdc14, a protein tyrosine phosphatase involved in the exit of cell mitosis and initiation of DNA replication, suggesting a role in cell cycle control. This protein has been shown to interact with, and dephosphorylate tumor suppressor protein p53, and is thought to regulate the function of p53. Alternative splicing of this gene results in several transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008],
细胞定位 ： Nucleus . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cytoplasm, cytoskeleton, spindle pole . Cytoplasm, cytoskeleton, spindle . Cell projection, kinocilium . Cell projection, stereocilium . Centrosomal during interphase, released into the cytoplasm at the onset of mitosis. Subsequently localizes to the mitotic spindle pole and at the central spindle (PubMed:12134069, PubMed:11901424, PubMed:15263015). Present along both the transient kinocilia of developing cochlear hair cells and the persistent kinocilia of vestibular hair cells (By similarity). .
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