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PCBP2 Polyclonal Antibody

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说明书下载
货号: PG8587
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
+

所属分类:


靶点: PCBP2
应用: WB,ELISA
反应性 : Human,Mouse
宿主物种 : Rabbit
MW(Observed): 40kD
同种型-Isotype : IgG

隐藏域元素占位

详细信息

推荐稀释比 : WB 1:500-2000;ELISA 1:5000-20000
组成 : PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal

抗原&靶点信息

特异性 : PCBP2 Polyclonal Antibody detects endogenous levels of protein.
基因名称 : PCBP2
蛋白名称 : Poly(rC)-binding protein 2 (Alpha-CP2) (Heterogeneous nuclear ribonucleoprotein E2) (hnRNP E2)

数据库链接:

Organism

基因 ID

SwissProt

Mouse
背景:

The protein encoded by this gene appears to be multifunctional. Along with PCBP-1 and hnRNPK, it is one of the major cellular poly(rC)-binding proteins. The encoded protein contains three K-homologous (KH) domains which may be involved in RNA binding. Together with PCBP-1, this protein also functions as a translational coactivator of poliovirus RNA via a sequence-specific interaction with stem-loop IV of the IRES, promoting poliovirus RNA replication by binding to its 5'-terminal cloverleaf structure. It has also been implicated in translational control of the 15-lipoxygenase mRNA, human papillomavirus type 16 L2 mRNA, and hepatitis A virus RNA. The encoded protein is also suggested to play a part in formation of a sequence-specific alpha-globin mRNP complex which is associated with alpha-globin mRNA stability. This multiexon structural mRNA is thought to be retrotransposed to generate

细胞定位 : Nucleus . Cytoplasm . Loosely bound in the nucleus. May shuttle between the nucleus and the cytoplasm.

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