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货号: PH0887
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
所属分类:
靶点: CD68
应用: IHC,IF
反应性 : Human,Mouse,Rat
宿主物种 : Mouse
MW(Observed): 37kD
同种型-Isotype : IgG2b,Kappa
隐藏域元素占位
详细信息
推荐稀释比 : IHC 1:200-400;IF 1:50-200
组成 : PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.
纯化工艺 : The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
克隆性 : Monoclonal
克隆号 : 6F3
抗原&靶点信息
特异性 : The antibody detects endogenous CD68 proteins.
基因名称 : CD68
蛋白名称 : Macrosialin
别名 : CD68;Macrosialin;Gp110;CD68
背景:
This gene encodes a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. The protein primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue- and organ-specific lectins or selectins. The protein is also a member of the scavenger receptor family. Scavenger receptors typically function to clear cellular debris, promote phagocytosis, and mediate the recruitment and activation of macrophages. Alternative splicing results in multiple transcripts encoding different isoforms. [provided by RefSeq, Jul 2008],


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