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TPP1 Polyclonal Antibody

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说明书下载
货号: PG6405
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
+

所属分类:


靶点: TPP1
应用: WB,ELISA
反应性 : Human,Rat,Mouse
宿主物种 : Rabbit
MW(Observed): 61kD
同种型-Isotype : IgG

隐藏域元素占位

详细信息

推荐稀释比 : WB 1:500-2000;ELISA 1:5000-20000
组成 : PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal

抗原&靶点信息

特异性 : TPP1 Polyclonal Antibody detects endogenous levels of protein.
基因名称 : TPP1 CLN2 GIG1 UNQ267/PRO304
蛋白名称 : Tripeptidyl-peptidase 1 (TPP-1) (Cell growth-inhibiting gene 1 protein) (Lysosomal pepstatin-insensitive protease) (LPIC) (Tripeptidyl aminopeptidase) (Tripeptidyl-peptidase I) (TPP-I)

数据库链接:

Organism

基因 ID

SwissProt

Mouse
背景:

This gene encodes a member of the sedolisin family of serine proteases. The protease functions in the lysosome to cleave N-terminal tripeptides from substrates, and has weaker endopeptidase activity. It is synthesized as a catalytically-inactive enzyme which is activated and auto-proteolyzed upon acidification. Mutations in this gene result in late-infantile neuronal ceroid lipofuscinosis, which is associated with the failure to degrade specific neuropeptides and a subunit of ATP synthase in the lysosome. [provided by RefSeq, Jul 2008],

细胞定位 : Lysosome . Melanosome . Identified by mass spectrometry in melanosome fractions from stage I to stage IV. .

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