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详细信息
推荐稀释比 : WB 1:500
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
克隆性 : Monoclonal
抗原&靶点信息
特异性 : This antibody detects endogenous levels of Lamin B2 and does not cross-react with related proteins.
基因名称 : Lamin B2
别名 : LAMB 2;LAMB2;Lamin-B2;LMN 2;LMN B2;LMN2;LMNB 2;LMNB2;LMNB2_HUMAN;MGC2721;RGD1563803.
背景:
lamin B2(LMNB2) Homo sapiens This gene encodes a B type nuclear lamin. The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. Mutations in this gene are associated with acquired partial lipodystrophy. [provided by RefSeq, May 2012],


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