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ITGAE (heavy chain, Cleaved-Ala179) rabbit pAb

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说明书下载
货号: PK0143
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
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靶点: ITGAE
应用: WB,IHC
反应性 : Human,Rat,Mouse,
宿主物种 : Rabbit
MW(Observed): 110kD,128kD
同种型-Isotype : IgG

隐藏域元素占位

详细信息

推荐稀释比 : WB 1:500-2000;IHC 1:50-300
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal

抗原&靶点信息

特异性 : This antibody detects endogenous levels of Human ITGAE (heavy chain, Cleaved-Ala179, protein was cleaved amino acid sequence between 178-179 )
基因名称 : ITGAE
蛋白名称 : ITGAE (heavy chain, Cleaved-Ala179)
别名 : Integrin alpha-E;HML-1 antigen;Integrin alpha-IEL;Mucosal lymphocyte 1 antigen;CD antigen CD103;[Cleaved into: Integrin alpha-E light chain;Integrin alpha-E heavy chain]

数据库链接:

Organism

基因 ID

SwissProt

背景:

integrin subunit alpha E(ITGAE) Homo sapiens Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes an I-domain-containing alpha integrin that undergoes post-translational cleavage in the extracellular domain, yielding disulfide-linked heavy and light chains. In combination with the beta 7 integrin, this protein forms the E-cadherin binding integrin known as the human mucosal lymphocyte-1 antigen. This protein is preferentially expressed in human intestinal intraepithelial lymphocytes (IEL), and in addition to a role in adhesion, it may serve as an accessory molecule for IEL activation. [provided by RefSeq, Jul 2008],

细胞定位 : Membrane; Single-pass type I membrane protein.

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