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Cleaved PARP Monoclonal Antibody(Mix)

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说明书下载
货号: PH0826
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
+


靶点: PARP
应用: IF,WB,IHC,
反应性 : Human
宿主物种 : Mouse
MW(Observed): 116,89kD

隐藏域元素占位

详细信息

推荐稀释比 : IF 1:50-200;WB 1:2000-5000;IHC 1:50-300
组成 : PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.
纯化工艺 : The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
克隆性 : Monoclonal

抗原&靶点信息

特异性 : The antibody detects endogenous pro and active PARP protein.
基因名称 : PARP1
蛋白名称 : Poly [ADP-ribose] polymerase 1
别名 : PARP1;ADPRT;PPOL;Poly [ADP-ribose] polymerase 1;PARP-1;ADP-ribosyltransferase diphtheria toxin-like 1;ARTD1;NAD;+;ADP-ribosyltransferase 1;ADPRT 1;Poly[ADP-ribose] synthase 1

数据库链接:

Organism

基因 ID

SwissProt

Mouse
背景:

This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes. [provided by RefSeq, Jul 2008],

细胞定位 : Nucleus . Nucleus, nucleolus . Chromosome . Localizes to sites of DNA damage. .

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