信号通路

联系我们

15392937510

地址:湖北省武汉市江夏区神墩四路 666 号武汉国英种业大厦A栋14F 
邮箱:pinuofei2017@163.com
TEL:15392937510

PARP-1 Polyclonal Antibody

复制产品信息

说明书下载
货号: PD1959
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
+


靶点: PARP
应用: IHC,IF,WB
反应性 : Human,Mouse,Rat
宿主物种 : Rabbit
MW(Observed): 113kD
同种型-Isotype : IgG

隐藏域元素占位

详细信息

推荐稀释比 : IHC 1:50-200;WB 1:500-2000;IF 1:50-200
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal

抗原&靶点信息

特异性 : This antibody detects endogenous levels of human PARP-1
基因名称 : PARP1 ADPRT PPOL
蛋白名称 : PARP-1
别名 : Poly [ADP-ribose] polymerase 1;PARP-1;ADP-ribosyltransferase diphtheria toxin-like 1;ARTD1;NAD;+;ADP-ribosyltransferase 1;ADPRT 1;Poly[ADP-ribose] synthase 1;

数据库链接:

Organism

基因 ID

SwissProt

背景:

This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes. [provided by RefSeq, Jul 2008],

细胞定位 : Nucleus . Nucleus, nucleolus . Chromosome . Localizes to sites of DNA damage. .

推荐产品

相关文献

留言咨询

留下您想咨询的信息,我们会尽快联系您

提交