信号通路

联系我们

15392937510

地址:湖北省武汉市江夏区神墩四路 666 号武汉国英种业大厦A栋14F 
邮箱:pinuofei2017@163.com
TEL:15392937510

CD276 (PN0562) Nb-FC recombinant antibody

复制产品信息

说明书下载
货号: PA0588
货期: 两个月
价格: 100ug/2200
+

所属分类:


靶点: CD366/TIM-3
应用: ELISA
反应性 : Human

隐藏域元素占位

详细信息

推荐稀释比 : ELISA 1:5000-100000
组成 : Phosphate-buffered solution
来源 : Camel, chimeric fusion of Nanobody (VHH) and mouse IgG1 Fc domain , recombinantly produced from 293F cell
纯化工艺 : Recombinant Expression and Affinity purified
储存 : -15°C to -25°C/1 year(Avoid freeze / thaw cycles)
浓度 : Please check the information on the tube
克隆性 : Monoclonal
克隆号 : PN0579

抗原&靶点信息

特异性 : This recombinant monoclonal antibody can detects endogenous levels of CD366/TIM-3 protein.
基因名称 : HAVCR2 TIM3 TIMD3
蛋白名称 : CD276 antigen (4Ig-B7-H3) (B7 homolog 3) (B7-H3) (Costimulatory molecule) (CD antigen CD276)
别名 : CD276;B7H3;PSEC0249;CD276 antigen;4Ig-B7-H3;B7 homolog 3;B7-H3;Costimulatory molecule;CD antigen CD276;CD276 nanobody;B7H3 nanobody;

数据库链接:

Organism

基因 ID

SwissProt

背景:

The protein encoded byThis gene belongs to the immunoglobulin superfamily, and TIM family of proteins. CD4-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas, Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases.This protein is a Th1-specific cell surface protein that regulates macrophage activation, and inhibits Th1-mediated auto- and alloimmune responses, and promotes immunological tolerance. [provided by RefSeq, Sep 2011]

细胞定位 : Membrane ; Single-pass type I membrane protein . Cell junction . Cell membrane . Localizes to the immunological synapse between CD8+ T-cells and target cells. .

推荐产品

相关文献

留言咨询

留下您想咨询的信息,我们会尽快联系您

提交