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CD276 (PN0395) Nb-FC recombinant antibody

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说明书下载
货号: PA0329
货期: 现货
价格: 100ug/2200
+


靶点: CD337
应用: ELISA
反应性 : Human

隐藏域元素占位

详细信息

推荐稀释比 : ELISA 1:5000-100000;Flow Cyt 1-2μg/Test
组成 : Phosphate-buffered solution
来源 : Camel, chimeric fusion of Nanobody (VHH) and mouse IgG1 Fc domain , recombinantly produced from 293F cell
纯化工艺 : Recombinant Expression and Affinity purified
储存 : -15°C to -25°C/1 year(Avoid freeze / thaw cycles)
浓度 : Please check the information on the tube
克隆性 : Monoclonal
克隆号 : PN0364

抗原&靶点信息

特异性 : This recombinant monoclonal antibody can detects endogenous levels of CD337 protein.
基因名称 : NCR3 1C7 LY117
蛋白名称 : CD276 antigen (4Ig-B7-H3) (B7 homolog 3) (B7-H3) (Costimulatory molecule) (CD antigen CD276)
别名 : CD276;B7H3;PSEC0249;CD276 antigen;4Ig-B7-H3;B7 homolog 3;B7-H3;Costimulatory molecule;CD antigen CD276;CD276 nanobody;B7H3 nanobody;

数据库链接:

Organism

基因 ID

SwissProt

背景:

The p30-15 monoclonal antibody recognizes CD337 also known as activating NK receptor NKp30 (NKp30), and natural cytotoxicity triggering receptor 3. NKp30 is a type I transmembrane protein, member of the natural cytotoxicity receptor family that contains one immunoglobulin-like domain. NKp30 has an apparent molecular weight of 30 kD and six isoforms are produced by alternative splicing. NKp30 is expressed on resting and activated NK cells. NKp30 enhances NK cell cytolysis of tumor cellts that are deficient in MHC class I molecules. NKp30 has been shown to associate with CD59 and TCRζ. The p30-15 antibody against human NKp30 has been shown to be useful for flow cytometry, stimulation of human NK cells via NKp30 in a redirected lysis assay, and blocking of NKp30 function in solution.

细胞定位 : Cell membrane ; Single-pass type I membrane protein .

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