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货号: PH1332
货期: 一周
价格: 100μL/2200
靶点: SOCS-3
应用: WB,IHC,IF
反应性 : Human,Pig
宿主物种 : Mouse
MW(CalcμLated) : 25kD
隐藏域元素占位
详细信息
推荐稀释比 : WB 1:1000-1:2000;IHC 1:500-1:1000;IF 1:50-200
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : Affinity purification
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
克隆性 : Monoclonal
抗原&靶点信息
特异性 : SOCS-3 Monoclonal Antibody detects endogenous levels of SOCS-3 protein.
基因名称 : SOCS3
蛋白名称 : Suppressor of cytokine signaling 3
别名 : SOCS3;CIS3;SSI3;Suppressor of cytokine signaling 3;SOCS-3;Cytokine-inducible SH2 protein 3;CIS-3;STAT-induced STAT inhibitor 3;SSI-3
背景:
This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene is induced by various cytokines, including IL6, IL10, and interferon (IFN)-gamma. The protein encoded by this gene can bind to JAK2 kinase, and inhibit the activity of JAK2 kinase. Studies of the mouse counterpart of this gene suggested the roles of this gene in the negative regulation of fetal liver hematopoiesis, and placental development. [provided by RefSeq, Jul 2008],


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