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Raptor (Phospho Ser863) rabbit pAb

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说明书下载
货号: PF0291
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
+


靶点: Raptor
应用: WB
反应性 : Human,Mouse,Rat
宿主物种 : Rabbit
MW(Observed): 150kD
同种型-Isotype : IgG

隐藏域元素占位

详细信息

修饰-Modification : Phospho
推荐稀释比 : WB 1:500-2000
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal

抗原&靶点信息

特异性 : This antibody detects endogenous levels of Raptor (Phospho-Ser863) at Human, Mouse,Rat
基因名称 : RPTOR KIAA1303 RAPTOR
蛋白名称 : Raptor (Phospho-Ser863)
别名 : Regulatory-associated protein of mTOR;Raptor;p150 target of rapamycin;TOR;-scaffold protein;

数据库链接:

Organism

基因 ID

SwissProt

Mouse
背景:

This gene encodes a component of a signaling pathway that regulates cell growth in response to nutrient and insulin levels. The encoded protein forms a stoichiometric complex with the mTOR kinase, and also associates with eukaryotic initiation factor 4E-binding protein-1 and ribosomal protein S6 kinase. The protein positively regulates the downstream effector ribosomal protein S6 kinase, and negatively regulates the mTOR kinase. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009],

细胞定位 : Cytoplasm. Lysosome. Cytoplasmic granule . Targeting to lysosomes depends on amino acid availability. In arsenite-stressed cells, accumulates in stress granules when associated with SPAG5 and association with lysosomes is drastically decreased.

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