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CD42d/GPV Polyclonal Antibody

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说明书下载
货号: PD2452
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
+


靶点: CD42d
应用: WB,IHC,IF,FC,ELISA
反应性 : Human,Mouse,Rat
宿主物种 : Rabbit
MW(Observed): 62kD
同种型-Isotype : IgG

隐藏域元素占位

详细信息

推荐稀释比 : WB 1:500-1:2000;IHC: 1:100-1:300;ELISA 1:10000;IF 1:50-200
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal

抗原&靶点信息

特异性 : CD42d Polyclonal Antibody detects endogenous levels of CD42d protein.
基因名称 : GP5
蛋白名称 : Platelet glycoprotein V
别名 : GP5;Platelet glycoprotein V;GPV;Glycoprotein 5;CD42d

数据库链接:

Organism

基因 ID

SwissProt

Mouse
背景:

Human platelet glycoprotein V (GP5) is a part of the Ib-V-IX system of surface glycoproteins that constitute the receptor for von Willebrand factor (VWF; MIM 613160) and mediate the adhesion of platelets to injured vascular surfaces in the arterial circulation, a critical initiating event in hemostasis. The main portion of the receptor is a heterodimer composed of 2 polypeptide chains, an alpha chain (GP1BA; MIM 606672) and a beta chain (GP1BB; MIM 138720), that are linked by disulfide bonds. The complete receptor complex includes noncovalent association of the alpha and beta subunits with platelet glycoprotein IX (GP9; MIM 173515) and GP5. Mutations in GP1BA, GP1BB, and GP9 have been shown to cause Bernard-Soulier syndrome (MIM 231200), a bleeding disorder (review by Lopez et al., 1998 [PubMed 9616133]).[supplied by OMIM, Nov 2010],

细胞定位 : Membrane; Single-pass type I membrane protein.

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