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CD117 (PN0365) Nb-FC recombinant antibody

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货号: PA0531
货期: 现货
价格: 100ug/2200
+

所属分类:


靶点: CD1A
应用: ELISA
反应性 : Human

隐藏域元素占位

详细信息

推荐稀释比 : ELISA 1:5000-100000
组成 : Phosphate-buffered solution
来源 : Camel, chimeric fusion of Nanobody (VHH) and mouse IgG1 Fc domain , recombinantly produced from 293F cell
纯化工艺 : Recombinant Expression and Affinity purified
储存 : -15°C to -25°C/1 year(Avoid freeze / thaw cycles)
浓度 : Please check the information on the tube
克隆性 : Monoclonal
克隆号 : PN0125

抗原&靶点信息

特异性 : This recombinant monoclonal antibody can detects endogenous levels of CD1A protein.
基因名称 : CD1A
蛋白名称 : Mast/stem cell growth factor receptor Kit (SCFR) (Piebald trait protein) (PBT) (Proto-oncogene c-Kit) (Tyrosine-protein kinase Kit) (p145 c-kit) (v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog) (CD antigen CD117)
别名 : C Kit;c-Kit;c-Kit Ligand;CD117;Kit;Kit Ligand;KIT oncogene;KIT proto oncogene receptor tyrosine kinase;KIT_HUMAN;Mast cell growth factor receptor;Mast/stem cell growth factor receptor Kit;MGF;p145 c-kit;PBT;Piebald trait protein;Proto oncogene c Kit;Proto oncogene tyrosine protein kinase Kit;Proto-oncogene c-Kit;SCF Receptor;SCFR;soluble KIT variant 1;Steel Factor Receptor;Stem cell factor receptor;tyrosine protein kinase Kit;Tyrosine-protein kinase Kit;v kit Hardy Zuckerman 4 feline sarcoma viral oncogene homolog;v kit Hardy Zuckerman 4 feline sarcoma viral oncogene like protein;v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog

数据库链接:

Organism

基因 ID

SwissProt

背景:

This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded byThis gene localizes to the plasma membrane and to recycling vesicles of the early endocytic system. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]

细胞定位 : Cell membrane ; Single-pass type I membrane protein . Membrane raft ; Single-pass type I membrane protein . Endosome membrane ; Single-pass type I membrane protein . Subject to intracellular trafficking between the cell membrane and endosomes (PubMed:11231314). Localizes to cell surface lipid rafts (PubMed:18178838). .

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