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SIK2 Polyclonal Antibody

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说明书下载
货号: PG6845
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
+


靶点: QIK/QSK
应用: WB,ELISA
反应性 : Human,Mouse
宿主物种 : Rabbit
MW(Observed): 101kD
同种型-Isotype : IgG

隐藏域元素占位

详细信息

推荐稀释比 : WB 1:500-2000;ELISA 1:5000-20000
组成 : PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal

抗原&靶点信息

特异性 : SIK2 Polyclonal Antibody detects endogenous levels of protein.
基因名称 : SIK2 KIAA0781 QIK SNF1LK2
蛋白名称 : Serine/threonine-protein kinase SIK2 (Qin-induced kinase) (Salt-inducible kinase 2) (SIK-2) (Serine/threonine-protein kinase SNF1-like kinase 2)
别名 : Serine/threonine-protein kinase SIK2;Qin-induced kinase;Salt-inducible kinase 2;SIK-2;Serine/threonine-protein kinase SNF1-like kinase 2;

数据库链接:

Organism

基因 ID

SwissProt

Mouse
背景:

catalytic activity:ATP + a protein = ADP + a phosphoprotein.,cofactor:Magnesium.,enzyme regulation:Activated by phosphorylation on Thr-175 by STK11 in complex with STE20-related adapter-alpha (STRAD alpha) pseudo kinase and CAB39.,function:Phosphorylates 'Ser-794' of IRS1 in insulin-stimulated adipocytes, potentially modulating the efficiency of insulin signal transduction. Inhibits CREB activity by phosphorylating and repressing TORCs, the CREB-specific coactivators.,similarity:Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. AMPK subfamily.,similarity:Contains 1 protein kinase domain.,similarity:Contains 1 UBA domain.,subunit:Interacts with and phosphorylates TORC2/CRTC2.,

细胞定位 : Cytoplasm . Endoplasmic reticulum membrane .

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