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货号: PL0155
货期: 现货
价格: 100μL/1800
所属分类:
靶点: PRKAR2A
应用: WB,IHC,IF,IP,ELISA
反应性 : Human
宿主物种 : Rabbit
MW(CalcμLated) : 46kD
MW(Observed): 54kD
同种型-Isotype : IgG,Kappa
隐藏域元素占位
详细信息
推荐稀释比 : IHC 1:1000-1:2000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
组成 : PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺 : Protein A
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
克隆号 : Monoclonal
抗原&靶点信息
特异性 : Endogenous
基因名称 : PRKAR2A
蛋白名称 : cAMP-dependent protein kinase type II-alpha regulatory subunit
别名 : PRKAR2A;PKR2;PRKAR2;cAMP-dependent protein kinase type II-alpha regulatory subunit
背景:
protein kinase cAMP-dependent type II regulatory subunit alpha(PRKAR2A) Homo sapiens cAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent protein kinase, which transduces the signal through phosphorylation of different target proteins. The inactive kinase holoenzyme is a tetramer composed of two regulatory and two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits have been identified in humans. The protein encoded by this gene is one of the regulatory subunits. This subunit can be phosphorylated by the activated catalytic subunit. It may interact with various A-kinase anchoring proteins and determine the subcellular localization of cAMP-dependent protein kinase. This subunit has b


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