信号通路

联系我们

15392937510

地址:湖北省武汉市江夏区神墩四路 666 号武汉国英种业大厦A栋14F 
邮箱:pinuofei2017@163.com
TEL:15392937510

GRK 2 Monoclonal Antibody

复制产品信息

说明书下载
货号: PH1645
货期: 一周
价格: 100μL/2200
+


靶点: GRK 2
应用: WB,IHC,IF,ELISA
反应性 : Human,Mouse,Rat,Monkey
宿主物种 : Mouse
MW(CalcμLated) : 80kD

隐藏域元素占位

详细信息

推荐稀释比 : WB 1:500-1:2000;IHC 1:200-1:1000;IF 1:200-1:1000;ELISA 1:10000;Not yet tested in other applications.
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : Affinity purification
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
克隆性 : Monoclonal

抗原&靶点信息

特异性 : GRK 2 Monoclonal Antibody detects endogenous levels of GRK 2 protein.
基因名称 : ADRBK1
蛋白名称 : Beta-adrenergic receptor kinase 1
别名 : ADRBK1;BARK;BARK1;GRK2;Beta-adrenergic receptor kinase 1;Beta-ARK-1;G-protein coupled receptor kinase 2

数据库链接:

Organism

基因 ID

SwissProt

Mouse
背景:

The product of this gene phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta-adrenergic and related G-protein-coupled receptors. Abnormal coupling of beta-adrenergic receptor to G protein is involved in the pathogenesis of the failing heart. [provided by RefSeq, Jul 2008],

细胞定位 : Cytoplasm . Cell membrane . Cell junction, synapse, postsynapse . Cell junction, synapse, presynapse .

推荐产品

相关文献

留言咨询

留下您想咨询的信息,我们会尽快联系您

提交