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货号: PG7649
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
靶点: AT2B3
应用: WB,ELISA
反应性 : Human,Rat
宿主物种 : Rabbit
MW(Observed): 134kD
同种型-Isotype : IgG
隐藏域元素占位
详细信息
推荐稀释比 : WB 1:500-2000;ELISA 1:5000-20000
组成 : PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal
抗原&靶点信息
特异性 : AT2B3 Polyclonal Antibody detects endogenous levels of protein.
基因名称 : ATP2B3
蛋白名称 : Plasma membrane calcium-transporting ATPase 3 (PMCA3) (Plasma membrane calcium ATPase isoform 3) (Plasma membrane calcium pump isoform 3)
背景:
The protein encoded by this gene belongs to the family of P-type primary ion transport ATPases characterized by the formation of an aspartyl phosphate intermediate during the reaction cycle. These enzymes remove bivalent calcium ions from eukaryotic cells against very large concentration gradients and play a critical role in intracellular calcium homeostasis. The mammalian plasma membrane calcium ATPase isoforms are encoded by at least four separate genes and the diversity of these enzymes is further increased by alternative splicing of transcripts. The expression of different isoforms and splice variants is regulated in a developmental, tissue- and cell type-specific manner, suggesting that these pumps are functionally adapted to the physiological needs of particular cells and tissues. This gene encodes the plasma membrane calcium ATPase isoform 3. Alternatively spliced tran


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