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UN13B rabbit pAb

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说明书下载
货号: PD1055
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
+

所属分类:


靶点: UN13B
应用: WB
反应性 : Human,Mouse,Rat
宿主物种 : Rabbit
MW(CalcμLated) : 175kD
同种型-Isotype : IgG

隐藏域元素占位

详细信息

推荐稀释比 : WB 1:500-2000
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal

抗原&靶点信息

特异性 : This antibody detects endogenous levels of UN13B at Human/Mouse/Rat
基因名称 : UNC13B UNC13
蛋白名称 : UN13B

数据库链接:

Organism

基因 ID

SwissProt

背景:

This gene is expressed in the kidney cortical epithelial cells and is upregulated by hyperglycemia. The encoded protein shares a high level of similarity to the rat homolog, and contains 3 C2 domains and a diacylglycerol-binding C1 domain. Hyperglycemia increases the levels of diacylglycerol, which has been shown to induce apoptosis in cells transfected with this gene and thus contribute to the renal cell complications of hyperglycemia. Studies in other species also indicate a role for this protein in the priming step of synaptic vesicle exocytosis. [provided by RefSeq, Jul 2008],

细胞定位 : Cytoplasm . Membrane ; Peripheral membrane protein . Cell membrane . Cell junction, synapse . Localized to synapses. Translocated to the plasma membrane in response to phorbol ester binding (By similarity). .

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