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货号: PH1790
货期: 一周
价格: 100μL/2200
所属分类:
靶点: CD10
应用: WB,IHC,IF,ELISA
反应性 : Human
宿主物种 : Mouse
MW(CalcμLated) : 86kD
隐藏域元素占位
详细信息
推荐稀释比 : WB 1:500-1:2000;IHC 1:200-1:1000;ELISA 1:10000;IF 1:50-200
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : Affinity purification
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
克隆性 : Monoclonal
抗原&靶点信息
特异性 : CD10 Monoclonal Antibody detects endogenous levels of CD10 protein.
基因名称 : MME
蛋白名称 : Neprilysin
别名 : MME;EPN;Neprilysin;Atriopeptidase;Common acute lymphocytic leukemia antigen;CALLA;Enkephalinase;Neutral endopeptidase 24.11;NEP;Neutral endopeptidase;Skin fibroblast elastase;SFE;CD antigen CD10
背景:
This gene encodes a common acute lymphocytic leukemia antigen that is an important cell surface marker in the diagnosis of human acute lymphocytic leukemia (ALL). This protein is present on leukemic cells of pre-B phenotype, which represent 85% of cases of ALL. This protein is not restricted to leukemic cells, however, and is found on a variety of normal tissues. It is a glycoprotein that is particularly abundant in kidney, where it is present on the brush border of proximal tubules and on glomerular epithelium. The protein is a neutral endopeptidase that cleaves peptides at the amino side of hydrophobic residues and inactivates several peptide hormones including glucagon, enkephalins, substance P, neurotensin, oxytocin, and bradykinin. This gene, which encodes a 100-kD type II transmembrane glycoprotein, exists in a single copy of greater than 45 kb. The 5' untranslated region of this


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