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NHERF-2 Polyclonal Antibody

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说明书下载
货号: PD2372
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
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靶点: NHERF-2
应用: WB,ELISA
反应性 : Human,Mouse,Rat
宿主物种 : Rabbit
MW(Observed): 37kD
同种型-Isotype : IgG

隐藏域元素占位

详细信息

推荐稀释比 : WB 1:500-1:2000;ELISA 1:10000;Not yet tested in other applications.
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal

抗原&靶点信息

特异性 : NHERF-2 Polyclonal Antibody detects endogenous levels of NHERF-2 protein.
基因名称 : SLC9A3R2
蛋白名称 : Na(+)/H(+) exchange regulatory cofactor NHE-RF2
别名 : SLC9A3R2;NHERF2;Na;+;/H;+;exchange regulatory cofactor NHE-RF2;NHERF-2;NHE3 kinase A regulatory protein E3KARP;SRY-interacting protein 1;SIP-1;Sodium-hydrogen exchanger regulatory factor 2;Solute carrier family 9 isoform A3 regulatory factor 2;Tyrosine kinase activator protein 1;TKA-1

数据库链接:

Organism

基因 ID

SwissProt

背景:

This gene encodes a member of the NHERF family of PDZ scaffolding proteins. These proteins mediate many cellular processes by binding to and regulating the membrane expression and protein-protein interactions of membrane receptors and transport proteins. The encoded protein plays a role in intestinal sodium absorption by regulating the activity of the sodium/hydrogen exchanger 3, and may also regulate the cystic fibrosis transmembrane regulator (CFTR) ion channel. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011],

细胞定位 : Endomembrane system ; Peripheral membrane protein . Nucleus . Apical cell membrane . Localizes with EZR and PODXL at the apical cell membrane of glomerular epithelium cells and the sides of the food processes (By similarity). Nuclear, in a punctate pattern. .

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