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推荐稀释比 ： ELISA 1:5000-100000;Flow Cyt 1-2μg/Test
组成 ： Phosphate-buffered solution
来源 ： Camel, chimeric fusion of Nanobody (VHH) and mouse IgG1 Fc domain , recombinantly produced from 293F cell
纯化工艺 ： Recombinant Expression and Affinity purified
储存 ： -15°C to -25°C/1 year(Avoid freeze / thaw cycles)
浓度 ： Please check the information on the tube
克隆性 ： Monoclonal
克隆号 ： PN0532
抗原&靶点信息
特异性 ： This recombinant monoclonal antibody can detects endogenous levels of CD16 protein.
基因名称 ： FCGR3A CD16A FCG3 FCGR3 IGFR3
蛋白名称 ： CD82 antigen (C33 antigen) (IA4) (Inducible membrane protein R2) (Metastasis suppressor Kangai-1) (Suppressor of tumorigenicity 6 protein) (Tetraspanin-27) (Tspan-27) (CD antigen CD82)
别名 ： 4F9 antibody;Antigen detected by monoclonal and antibody IA4 antibody;C33 antibody;C33 antigen antibody;CD 82 antibody;CD82 antibody;CD82 antigen antibody;CD82 molecule antibody;CD82_HUMAN antibody;GR 15 antibody;GR15 antibody;IA 4 antibody;IA4 antibody;Inducible membrane protein antibody;Inducible membrane protein R2 antibody;KAI 1 antibody;KAI1 antibody;Kangai 1;suppression of tumorigenicity 6;prostate;CD82 antigen;R2 leukocyte antigen;antigen detected by monoclonal and antibody IA4;antibody;Kangai 1 antibody;Kangai1 antibody;Leukocyte surface antigen R2 antibody;Metastasis suppressor Kangai 1 antibody;Metastasis suppressor Kangai-1 antibody;Metastasis suppressor Kangai1 antibody;Prostate cancer antimetastasis gene KAI1 antibody;R2 antibody;R2 leukocyte antigen antibody;SAR 2 antibody;SAR2 antibody;ST 6 antibody;ST6 antibody;Suppression of tumorigenicity 6 antibody;Suppression of tumorigenicity 6 prostate antibody;Suppressor of tumorigenicity 6 antibody;Suppressor of tumorigenicity 6 protein antibody;Tetraspanin 27 antibody;Tetraspanin-27 antibody;Tetraspanin27 antibody;Tspan 27 antibody;Tspan-27 antibody;Tspan27 antibody;CD82 nanobody;
背景：
This gene encodes a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody complexes from the circulation, as well as other other antibody-dependent responses.This gene (FCGR3A) is highly similar to another nearby gene (FCGR3B) located on chromosome 1. The receptor encoded byThis gene is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide, whereas FCGR3B is expressed on polymorphonuclear neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI) linkage. Mutations inThis gene have been linked to susceptibility to recurrent viral infections, susceptibility to systemic lupus erythematosus, and alloimmune neonatal neutropenia. Alternatively spliced transcript variants encoding different isoforms have been found forThis gene. [provided by RefSeq,
细胞定位 ： Cell membrane ; Single-pass type I membrane protein . Secreted . Exists also as a soluble receptor. .
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