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CD158a Polyclonal Antibody

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说明书下载
货号: PD2425
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
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靶点: CD158a
应用: WB,ELISA
反应性 : Human
宿主物种 : Rabbit
MW(Observed): 39kD
同种型-Isotype : IgG

隐藏域元素占位

详细信息

推荐稀释比 : WB 1:500-1:2000;ELISA 1:10000;Not yet tested in other applications.
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal

抗原&靶点信息

特异性 : CD158a Polyclonal Antibody detects endogenous levels of CD158a protein.
基因名称 : KIR2DL1
蛋白名称 : Killer cell immunoglobulin-like receptor 2DL1
别名 : KIR2DL1;CD158A;NKAT1;Killer cell immunoglobulin-like receptor 2DL1;CD158 antigen-like family member A;MHC class I NK cell receptor;Natural killer-associated transcript 1;NKAT-1;p58 natural killer cell receptor clones CL-42/47.11;p58 NK receptor CL-42/47.11;p58.1 MHC class-I-specific NK receptor;CD158a

数据库链接:

Organism

基因 ID

SwissProt

背景:

Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several "framework" genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the

细胞定位 : Cell membrane ; Single-pass type I membrane protein.

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