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货号: PD6233
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
所属分类:
靶点: CRSP34
应用: WB,ELISA
反应性 : Human,Mouse
宿主物种 : Rabbit
MW(Observed): 35kD
同种型-Isotype : IgG
隐藏域元素占位
详细信息
推荐稀释比 : WB 1:500-1:2000;ELISA 1:10000;Not yet tested in other applications.
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal
抗原&靶点信息
特异性 : CRSP34 Polyclonal Antibody detects endogenous levels of CRSP34 protein.
基因名称 : MED27
蛋白名称 : Mediator of RNA polymerase II transcription subunit 27
别名 : MED27;CRSP34;CRSP8;Mediator of RNA polymerase II transcription subunit 27;Cofactor required for Sp1 transcriptional activation subunit 8;CRSP complex subunit 8;Mediator complex subunit 27;P37 TRAP/SMCC/PC2 subunit;Transcriptional co
背景:
The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 5. [provided by RefSeq, Dec 2011],


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