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Calnexin Monoclonal Antibody

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说明书下载
货号: PH1799
货期: 一周
价格: 100μL/2200
+


靶点: Calnexin
应用: WB,IF,ELISA
反应性 : Human
宿主物种 : Mouse
MW(CalcμLated) : 68kD

隐藏域元素占位

详细信息

推荐稀释比 : WB 1:500-1:2000;IF 1:200-1:1000;ELISA 1:10000;Not yet tested in other applications.
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : Affinity purification
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
克隆性 : Monoclonal

抗原&靶点信息

特异性 : Calnexin Monoclonal Antibody detects endogenous levels of Calnexin protein.
基因名称 : CANX
蛋白名称 : Calnexin
别名 : CANX;Calnexin;IP90;Major histocompatibility complex class I antigen-binding protein p88;p90

数据库链接:

Organism

基因 ID

SwissProt

Mouse
背景:

This gene encodes a member of the calnexin family of molecular chaperones. The encoded protein is a calcium-binding, endoplasmic reticulum (ER)-associated protein that interacts transiently with newly synthesized N-linked glycoproteins, facilitating protein folding and assembly. It may also play a central role in the quality control of protein folding by retaining incorrectly folded protein subunits within the ER for degradation. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq, Jul 2008],

细胞定位 : Endoplasmic reticulum membrane ; Single-pass type I membrane protein . Endoplasmic reticulum . Melanosome . Identified by mass spectrometry in melanosome fractions from stage I to stage IV (PubMed:12643545, PubMed:17081065). The palmitoylated form preferentially localizes to the perinuclear rough ER (PubMed:22314232). .

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