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货号: PF0199
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
所属分类:
靶点: NACA
应用: WB
反应性 : Human,Mouse,Rat
宿主物种 : Rabbit
MW(Observed): 23kD
同种型-Isotype : IgG
隐藏域元素占位
详细信息
修饰-Modification : Phospho
推荐稀释比 : WB 1:500-2000
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal
抗原&靶点信息
特异性 : This antibody detects endogenous levels of NACA (Phospho-Thr159) at Human, Mouse,Rat
基因名称 : NACA HSD48
蛋白名称 : NACA (Phospho-Thr159)
别名 : NACA;HSD48;Nascent polypeptide-associated complex subunit alpha;NAC-alpha;Alpha-NAC;allergen Hom s 2
背景:
This gene encodes a protein that associates with basic transcription factor 3 (BTF3) to form the nascent polypeptide-associated complex (NAC). This complex binds to nascent proteins that lack a signal peptide motif as they emerge from the ribosome, blocking interaction with the signal recognition particle (SRP) and preventing mistranslocation to the endoplasmic reticulum. This protein is an IgE autoantigen in atopic dermatitis patients. Alternative splicing results in multiple transcript variants, but the full length nature of some of these variants, including those encoding very large proteins, has not been determined. There are multiple pseudogenes of this gene on different chromosomes. [provided by RefSeq, Feb 2016],


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