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ACE2 Rabbit pAb

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说明书下载
货号: PG3199
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
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靶点: ACE2
应用: IHC,WB
反应性 : Human,Mouse,Rat
宿主物种 : Rabbit
MW(Observed): 120-135kD
同种型-Isotype : IgG

隐藏域元素占位

详细信息

推荐稀释比 : IHC1:50-200;WB 1:1000-2000
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal

抗原&靶点信息

特异性 : This antibody detects endogenous levels of ACE2 at Human, Mouse,Rat
基因名称 : ACE2 UNQ868/PRO1885
蛋白名称 : ACE2
别名 : Angiotensin-converting enzyme 2;ACE-related carboxypeptidase;Angiotensin-converting enzyme homolog;ACEH;Metalloprotease MPROT15;[Cleaved into: Processed angiotensin-converting enzyme 2]

数据库链接:

Organism

基因 ID

SwissProt

背景:

angiotensin I converting enzyme 2(ACE2) Homo sapiens The protein encoded by this gene belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. The organ- and cell-specific expression of this gene suggests that it may play a role in the regulation of cardiovascular and renal function, as well as fertility. In addition, the encoded protein is a functional receptor for the spike glycoprotein of the human coronaviruses SARS and HCoV-NL63.

细胞定位 : [Processed angiotensin-converting enzyme 2]: Secreted .; Cell membrane ; Single-pass type I membrane protein . Cytoplasm . Cell projection, cilium . Apical cell membrane . Detected in both cell membrane and cytoplasm in neurons. .; [Isoform 2]: Apical cell membrane .

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