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货号: PG3314
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
所属分类:
靶点: MEK-5
应用: WB,IHC,IF
反应性 : Human,Mouse,Rat
宿主物种 : Rabbit
MW(Observed): 49kD
同种型-Isotype : IgG
隐藏域元素占位
详细信息
推荐稀释比 : WB 1:1000-2000;IHC 1:200-500;IF 1:50-200
组成 : PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
克隆性 : Polyclonal
抗原&靶点信息
特异性 : The antibody detects endogenous MEK-5 protein.
基因名称 : MAP2K5
蛋白名称 : Dual specificity mitogen-activated protein kinase kinase 5
别名 : MAP2K5;MEK5;MKK5;PRKMK5;Dual specificity mitogen-activated protein kinase kinase 5;MAP kinase kinase 5;MAPKK 5;MAPK/ERK kinase 5;MEK 5
背景:
The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically interacts with and activates MAPK7/ERK5. This kinase itself can be phosphorylated and activated by MAP3K3/MEKK3, as well as by atypical protein kinase C isoforms (aPKCs). The signal cascade mediated by this kinase is involved in growth factor stimulated cell proliferation and muscle cell differentiation. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been described. [provided by RefSeq, May 2011],


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