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货号: PH0595
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
所属分类:
靶点: PLAUR
应用: WB,IF,ELISA
反应性 : Human,
宿主物种 : Mouse
MW(CalcμLated) : 37kD
MW(Observed): 37kD
同种型-Isotype : IgG2b,Kappa
隐藏域元素占位
详细信息
推荐稀释比 : WB 1:500-2000;IF 1:100-500;ELISA 1:1000-5000
组成 : PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺 : Protein G
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Monoclonal
克隆号 : PT2194
抗原&靶点信息
特异性 : This antibody detects endogenous levels of uPAR protein.
基因名称 : PLAUR MO3 UPAR
蛋白名称 : Urokinase plasminogen activator surface receptor (U-PAR) (uPAR) (Monocyte activation antigen Mo3) (CD antigen CD87)
别名 : PLAUR;MO3;UPAR;Urokinase plasminogen activator surface receptor;U-PAR;uPAR;Monocyte activation antigen Mo3;CD antigen CD87
背景:
plasminogen activator, urokinase receptor(PLAUR) Homo sapiens This gene encodes the receptor for urokinase plasminogen activator and, given its role in localizing and promoting plasmin formation, likely influences many normal and pathological processes related to cell-surface plasminogen activation and localized degradation of the extracellular matrix. It binds both the proprotein and mature forms of urokinase plasminogen activator and permits the activation of the receptor-bound pro-enzyme by plasmin. The protein lacks transmembrane or cytoplasmic domains and may be anchored to the plasma membrane by a glycosyl-phosphatidylinositol (GPI) moiety following cleavage of the nascent polypeptide near its carboxy-terminus. However, a soluble protein is also produced in some cell types. Alternative splicing results in multiple transcript variants encoding different isoforms. The proprotein experiences several post-translational cleavage reacti


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