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CD8A rabbit pAb

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说明书下载
货号: PD0255
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
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靶点: CD8
应用: WB,ELISA
反应性 : Human,Rat,Mouse,
宿主物种 : Rabbit
MW(CalcμLated) : 26kD
同种型-Isotype : IgG

隐藏域元素占位

详细信息

推荐稀释比 : WB 1:1000-2000;ELISA 1:5000-20000
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal

抗原&靶点信息

特异性 : This antibody detects endogenous levels of Human CD8A
基因名称 : CD8A MAL
蛋白名称 : CD8A
别名 : T-cell surface glycoprotein CD8 alpha chain;T-lymphocyte differentiation antigen T8/Leu-2;CD antigen CD8a;

数据库链接:

Organism

基因 ID

SwissProt

背景:

The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011],

细胞定位 : [Isoform 1]: Cell membrane ; Single-pass type I membrane protein. CD8A localizes to lipid rafts only when associated with its partner CD8B. .; [Isoform 2]: Secreted .

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