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CD94 (PN0238) Nb-FC recombinant antibody

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说明书下载
货号: PA0480
货期: 现货
价格: 100ug/2200
+


靶点: CD8
应用: ELISA
反应性 : Human

隐藏域元素占位

详细信息

推荐稀释比 : ELISA 1:5000-100000;Flow Cyt 1-2μg/Test
组成 : Phosphate-buffered solution
来源 : Camel, chimeric fusion of Nanobody (VHH) and mouse IgG1 Fc domain , recombinantly produced from 293F cell
纯化工艺 : Recombinant Expression and Affinity purified
储存 : -15°C to -25°C/1 year(Avoid freeze / thaw cycles)
浓度 : Please check the information on the tube
克隆性 : Monoclonal
克隆号 : PN0558

抗原&靶点信息

特异性 : This recombinant monoclonal antibody can detects endogenous levels of CD8 protein.
基因名称 : CD8A MAL
蛋白名称 : Natural killer cells antigen CD94 (KP43) (Killer cell lectin-like receptor subfamily D member 1) (NK cell receptor) (CD antigen CD94)
别名 : KLRD1;CD94;Natural killer cells antigen CD94;KP43;Killer cell lectin-like receptor subfamily D member 1;NK cell receptor;CD antigen CD94;CD94 nanobody;

数据库链接:

Organism

基因 ID

SwissProt

背景:

The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains.This gene encodes the CD8 alpha chain. Multiple transcript variants encoding different isoforms have been found forThis gene. [provided by RefSeq, Nov 2011]

细胞定位 : [Isoform 1]: Cell membrane ; Single-pass type I membrane protein. CD8A localizes to lipid rafts only when associated with its partner CD8B. .; [Isoform 2]: Secreted .

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