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Erbin rabbit pAb

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说明书下载
货号: PD0309
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
+


靶点: Erbin
应用: WB,ELISA
反应性 : Human,Mouse
宿主物种 : Rabbit
MW(CalcμLated) : 155kD
同种型-Isotype : IgG

隐藏域元素占位

详细信息

推荐稀释比 : WB 1:1000-2000;ELISA 1:5000-20000
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal

抗原&靶点信息

特异性 : This antibody detects endogenous levels of Human Erbin Polyclonal Antibody
基因名称 : ERBB2IP ERBIN KIAA1225 LAP2
蛋白名称 : Erbin Polyclonal Antibody
别名 : ERBB2IP;ERBIN;KIAA1225;LAP2;Protein LAP2;Densin-180-like protein;Erbb2-interacting protein;Erbin

数据库链接:

Organism

基因 ID

SwissProt

背景:

This gene is a member of the leucine-rich repeat and PDZ domain (LAP) family. The encoded protein contains 17 leucine-rich repeats and one PDZ domain. It binds to the unphosphorylated form of the ERBB2 protein and regulates ERBB2 function and localization. It has also been shown to affect the Ras signaling pathway by disrupting Ras-Raf interaction. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011],

细胞定位 : Cell junction, hemidesmosome . Nucleus membrane . Basolateral cell membrane . Found in hemidesmosomes, which are cell-substrate adhesion complexes in stratified epithelia. In transfected cells, either diffusely distributed over the cytoplasm or concentrated at the basolateral membrane. Colocalizes with the adrenergic receptors, ADREN1A and ADREN1B, at the nuclear membrane of cardiac myocytes (By similarity). .

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