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推荐稀释比 ： ELISA 1:5000-100000
组成 ： Phosphate-buffered solution
来源 ： Camel, chimeric fusion of Nanobody (VHH) and mouse IgG1 Fc domain , recombinantly produced from 293F cell
纯化工艺 ： Recombinant Expression and Affinity purified
储存 ： -15°C to -25°C/1 year(Avoid freeze / thaw cycles)
浓度 ： Please check the information on the tube
克隆性 ： Monoclonal
克隆号 ： PN0542
抗原&靶点信息
特异性 ： This recombinant monoclonal antibody can detects endogenous levels of CD45 protein.
基因名称 ： PTPRC CD45
蛋白名称 ： HLA class II histocompatibility antigen, DR alpha chain (MHC class II antigen DRA)
别名 ： DASS-397D15.1 antibody;DR alpha chain antibody;DR alpha chain precursor antibody;DRA_HUMAN antibody;DRB1 antibody;DRB4 antibody;FLJ51114 antibody;Histocompatibility antigen HLA DR alpha antibody;Histocompatibility antigen HLA-DR alpha antibody;HLA class II histocompatibility antigen antibody;HLA class II histocompatibility antigen DR alpha chain antibody;HLA DR1B antibody;HLA DR3B antibody;HLA DRA antibody;HLA DRA1 antibody;HLA DRB1 antibody;HLA DRB3 antibody;HLA DRB4 antibody;HLA DRB5 antibody;HLA-DR histocompatibility type antibody;HLA-DRA antibody;HLADR4B antibody;HLADRA1 antibody;HLADRB antibody;Major histocompatibility complex class II DR alpha antibody;Major histocompatibility complex class II DR beta 1 antibody;Major histocompatibility complex class II DR beta 3 antibody;Major histocompatibility complex class II DR beta 4 antibody;Major histocompatibility complex class II DR beta 5 antibody;MGC117330 antibody;MHC cell surface glycoprotein antibody;MHC class II antigen DRA antibody;MHC II antibody;MLRW antibody;OTTHUMP00000029406 antibody;OTTHUMP00000029407 antibody;HLA-DRA nanobody;
背景：
The protein encoded byThis gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation.This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP.This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling.This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling. Alternatively spliced transcripts variants ofThis gene, which enc
细胞定位 ： Cell membrane ; Single-pass type I membrane protein . Membrane raft . Colocalized with DPP4 in membrane rafts. .
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