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推荐稀释比 ： ELISA 1:5000-100000
组成 ： Phosphate-buffered solution
来源 ： Camel, chimeric fusion of Nanobody (VHH) and mouse IgG1 Fc domain , recombinantly produced from 293F cell
纯化工艺 ： Recombinant Expression and Affinity purified
储存 ： -15°C to -25°C/1 year(Avoid freeze / thaw cycles)
浓度 ： Please check the information on the tube
克隆性 ： Monoclonal
克隆号 ： PN0582
抗原&靶点信息
特异性 ： This recombinant monoclonal antibody can detects endogenous levels of CD276/B7H3 protein.
基因名称 ： CD276 B7H3 PSEC0249 UNQ309/PRO352
蛋白名称 ： Interleukin-1 beta (IL-1 beta) (Catabolin)
别名 ： IL-1;IL1F2;IL1beta;IL1-BETA;Catabolin antibody;H1 antibody;IFN beta inducing factor antibody;IL 1 antibody;IL 1 beta antibody;IL-1 beta antibody;IL1 antibody;IL1 BETA antibody;IL1B antibody;IL1B_HUMAN antibody;IL1F2 antibody;Interleukin 1 beta antibody;Interleukin 1 beta precursor antibody;interleukin 1;beta antibody;Interleukin-1 beta antibody;OAF antibody;Osteoclast activating factor antibody;OTTHUMP00000162031 antibody;Preinterleukin 1 beta antibody;Preinterleukin beta antibody;Pro interleukin 1 beta antibody;IL-1β;IL-1B nanobody;
背景：
The protein encoded byThis gene belongs to the immunoglobulin superfamily, and thought to participate in the regulation of T-cell-mediated immune response. Studies show that while the transcript ofThis gene is ubiquitously expressed in normal tissues and solid tumors, the protein is preferentially expressed only in tumor tissues. Additionally, it was observed that the 3' UTR ofThis transcript contains a target site for miR29 microRNA, and there is an inverse correlation between the expression ofThis protein and miR29 levels, suggesting regulation of expression ofThis gene product by miR29. Alternatively spliced transcript variants encoding different isoforms have been found forThis gene. [provided by RefSeq, Sep 2011]
细胞定位 ： Membrane ; Single-pass type I membrane protein .
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