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Beclin-1 (Phospho Ser93/96) Rabbit pAb

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说明书下载
货号: PF0123
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
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靶点: Beclin 1
应用: IHC,WB
反应性 : Human,Mouse,Rat
宿主物种 : Rabbit
MW(Observed): 55kD

隐藏域元素占位

详细信息

修饰-Modification : Phospho
推荐稀释比 : WB 1:500-2000;IHC 1:50-200
组成 : PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺 : The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal

抗原&靶点信息

特异性 : This antibody detects endogenous levels of Beclin-1 (Phospho Ser93/96) Rabbit pAb at Human, Mouse,Rat
基因名称 : BECN1 GT197
蛋白名称 : Beclin-1 (Coiled-coil myosin-like BCL2-interacting protein) (Protein GT197)
别名 : Beclin-1;Coiled-coil myosin-like BCL2-interacting protein;Protein GT197;

数据库链接:

Organism

基因 ID

SwissProt

背景:

beclin 1(BECN1) Homo sapiens This gene encodes a protein that regulates autophagy, a catabolic process of degradation induced by starvation. The encoded protein is a component of the phosphatidylinositol-3-kinase (PI3K) complex which mediates vesicle-trafficking processes. This protein is thought to play a role in multiple cellular processes, including tumorigenesis, neurodegeneration and apoptosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015],

细胞定位 : Cytoplasm . Golgi apparatus, trans-Golgi network membrane ; Peripheral membrane protein . Endosome membrane ; Peripheral membrane protein . Endoplasmic reticulum membrane ; Peripheral membrane protein . Mitochondrion membrane ; Peripheral membrane protein . Endosome . Cytoplasmic vesicle, autophagosome . Interaction with ATG14 promotes translocation to autophagosomes. Expressed in dendrites and cell bodies of cerebellar Purkinje cells (By similarity). .; [Beclin-1-C 35 kDa]: Mitochondrion . Nucleus . Cytoplasm .; [Beclin-1-C 37 kDa]: Mitochondrion .

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