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ITGA5 (heavy chain, Cleaved-Arg894) rabbit pAb

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说明书下载
货号: PK0146
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
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靶点: Integrin α5
应用: WB,ELISA,IHC
反应性 : Human,Mouse
宿主物种 : Rabbit
MW(Observed): 94kD,110kD
同种型-Isotype : IgG

隐藏域元素占位

详细信息

推荐稀释比 : WB 1:500-2000;IHC 1:50-300;ELISA 1:2000-20000
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal

抗原&靶点信息

特异性 : This antibody detects endogenous levels of Human,Mouse ITGA5 (heavy chain, Cleaved-Arg894, protein was cleaved amino acid sequence between 894-895 )
基因名称 : ITGA5 FNRA
蛋白名称 : ITGA5 (heavy chain, Cleaved-Arg894)
别名 : Integrin alpha-5;CD49 antigen-like family member E;Fibronectin receptor subunit alpha;Integrin alpha-F;VLA-5;CD antigen CD49e;[Cleaved into: Integrin alpha-5 heavy chain;Integrin alpha-5 light chain]

数据库链接:

Organism

基因 ID

SwissProt

背景:

function:Integrin alpha-5/beta-1 is a receptor for fibronectin and fibrinogen. It recognizes the sequence R-G-D in its ligands. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions.,similarity:Belongs to the integrin alpha chain family.,similarity:Contains 7 FG-GAP repeats.,subunit:Heterodimer of an alpha and a beta subunit. The alpha subunit is composed of an heavy and a light chain linked by a disulfide bond. Alpha-5 associates with beta-1. Interacts with HPS5 and NISCH. Interacts with HIV-1 Tat. Interacts with RAB21.,

细胞定位 : Membrane; Single-pass type I membrane protein. Cell junction, focal adhesion . Cell surface .

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