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GRP78 BiP Polyclonal Antibody

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说明书下载
货号: PD2233
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
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靶点: HSP A5/GRP78
应用: WB,IHC,IF,ELISA
反应性 : Human,Mouse,Rat,Fish
宿主物种 : Rabbit
MW(Observed): 78kD
同种型-Isotype : IgG

隐藏域元素占位

详细信息

推荐稀释比 : WB 1:500-1:2000;IHC-f:1:50-300;ELISA 1:10000-20000;IF 1:50-200
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal

抗原&靶点信息

特异性 : The antibody detects endogenous GRP78 BiP
基因名称 : HSPA5 GRP78
蛋白名称 : GRP78 BiP
别名 : 78 kDa glucose-regulated protein;GRP-78;Endoplasmic reticulum lumenal Ca;2+;-binding protein grp78;Heat shock 70 kDa protein 5;Immunoglobulin heavy chain-binding protein;BiP;

数据库链接:

Organism

基因 ID

SwissProt

背景:

The protein encoded by this gene is a member of the heat shock protein 70 (HSP70) family. It is localized in the lumen of the endoplasmic reticulum (ER), and is involved in the folding and assembly of proteins in the ER. As this protein interacts with many ER proteins, it may play a key role in monitoring protein transport through the cell.[provided by RefSeq, Sep 2010],

细胞定位 : Endoplasmic reticulum lumen . Melanosome . Cytoplasm . Cell surface . Identified by mass spectrometry in melanosome fractions from stage I to stage IV (PubMed:12643545). Localizes to the cell surface of epithelial cells in response to high levels of free iron (PubMed:20484814, PubMed:24355926, PubMed:27159390). .

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