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货号: PG3188
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
所属分类:
靶点: STIP1/HOP
应用: IHC,WB
反应性 : Human,Mouse,Rat
宿主物种 : Rabbit
MW(Observed): 64kD
同种型-Isotype : IgG
隐藏域元素占位
详细信息
推荐稀释比 : IHC1:50-200;WB 1:1000-2000
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal
抗原&靶点信息
特异性 : This antibody detects endogenous levels of STIP1/HOP at Human, Mouse,Rat
基因名称 : STIP1
蛋白名称 : STIP1/HOP
别名 : Stress-induced-phosphoprotein 1;STI1;Hsc70/Hsp90-organizing protein;Hop;Renal carcinoma antigen NY-REN-11;Transformation-sensitive protein IEF SSP 3521;
背景:
STIP1 is an adaptor protein that coordinates the functions of HSP70 (see HSPA1A; MIM 140550) and HSP90 (see HSP90AA1; MIM 140571) in protein folding. It is thought to assist in the transfer of proteins from HSP70 to HSP90 by binding both HSP90 and substrate-bound HSP70. STIP1 also stimulates the ATPase activity of HSP70 and inhibits the ATPase activity of HSP90, suggesting that it regulates both the conformations and ATPase cycles of these chaperones (Song and Masison, 2005 [PubMed 16100115]).[supplied by OMIM, Jul 2009],


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