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EGF Polyclonal Antibody

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说明书下载
货号: PD2218
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
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靶点: EGF
应用: WB,IHC,IF,ELISA
反应性 : Human,Mouse,
宿主物种 : Rabbit
MW(Observed): 130kD
同种型-Isotype : IgG

隐藏域元素占位

详细信息

推荐稀释比 : WB 1:500-2000;IHC 1:500-200;ELISA 1:10000-20000;IF 1:50-200
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal

抗原&靶点信息

特异性 : The antibody detects endogenous EGF
基因名称 : EGF
蛋白名称 : Pro-epidermal growth factor (EGF) [Cleaved into: Epidermal growth factor (Urogastrone)]
别名 : Pro-epidermal growth factor;EGF;[Cleaved into: Epidermal growth factor;Urogastrone;]

数据库链接:

Organism

基因 ID

SwissProt

背景:

This gene encodes a member of the epidermal growth factor superfamily. The encoded preproprotein is proteolytically processed to generate the 53-amino acid epidermal growth factor peptide. This protein acts a potent mitogenic factor that plays an important role in the growth, proliferation and differentiation of numerous cell types. This protein acts by binding with high affinity to the cell surface receptor, epidermal growth factor receptor. Defects in this gene are the cause of hypomagnesemia type 4. Dysregulation of this gene has been associated with the growth and progression of certain cancers. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed. [provided by RefSeq, Jan 2016],

细胞定位 : Membrane; Single-pass type I membrane protein.

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