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货号: PD2149
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
所属分类:
靶点: IFN-β
应用: IHC,IF,ELISA
反应性 : Human,Rat,Mouse,
宿主物种 : Rabbit
同种型-Isotype : IgG
隐藏域元素占位
详细信息
推荐稀释比 : IHC 1:50-200;ELISA 1:10000-20000;IF 1:50-200
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal
抗原&靶点信息
特异性 : The antibody detects endogenous IFN-β
基因名称 : IFNB1 IFB IFNB
蛋白名称 : Interferon beta (IFN-beta) (Fibroblast interferon)
别名 : Interferon beta;IFN-beta;Fibroblast interferon;
背景:
This gene encodes a cytokine that belongs to the interferon family of signaling proteins, which are released as part of the innate immune response to pathogens. The protein encoded by this gene belongs to the type I class of interferons, which are important for defense against viral infections. In addition, type I interferons are involved in cell differentiation and anti-tumor defenses. Following secretion in response to a pathogen, type I interferons bind a homologous receptor complex and induce transcription of genes such as those encoding inflammatory cytokines and chemokines. Overactivation of type I interferon secretion is linked to autoimmune diseases. Mice deficient for this gene display several phenotypes including defects in B cell maturation and increased susceptibility to viral infection. [provided by RefSeq, Sep 2015],


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