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Tuberin (Phospho Thr1462) Rabbit mAb

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说明书下载
货号: PL0354
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
+


靶点: Tuberin
应用: WB,IHC,IF,ELISA
反应性 : Human,Mouse
宿主物种 : Rabbit
MW(CalcμLated) : 201kD
MW(Observed): 201kD
同种型-Isotype : IgG,Kappa

隐藏域元素占位

详细信息

修饰-Modification : Phospho
推荐稀释比 : IHC 1:100-1:200;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;
组成 : PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺 : Protein A
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
克隆号 : Monoclonal

抗原&靶点信息

特异性 : Tuberin (Phospho Thr1462) Antibody detects endogenous levels of Tuberin protein only when phosphorylated at T1462.The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):GYtIS
基因名称 : TSC2 TSC4
蛋白名称 : Tuberin
别名 : TSC2;TSC4;Tuberin;Tuberous sclerosis 2 protein

数据库链接:

Organism

基因 ID

SwissProt

Mouse
背景:

Mutations in this gene lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008],

细胞定位 : Cytoplasm. Membrane; Peripheral membrane protein. At steady state found in association with membranes.

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