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IKKε Monoclonal Antibody

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说明书下载
货号: PH1613
货期: 一周
价格: 100μL/2200

详细信息

推荐稀释比 : WB 1:500-1:2000;ELISA 1:10000;Not yet tested in other applications.
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : Affinity purification
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
克隆性 : Monoclonal

抗原&靶点信息

特异性 : IKKε Monoclonal Antibody detects endogenous levels of IKKε protein.
基因名称 : IKBKE
蛋白名称 : Inhibitor of nuclear factor kappa-B kinase subunit epsilon
别名 : IKBKE;IKKE;IKKI;KIAA0151;Inhibitor of nuclear factor kappa-B kinase subunit epsilon;I-kappa-B kinase epsilon;IKK-E;IKK-epsilon;IkBKE;Inducible I kappa-B kinase;IKK-i

数据库链接:

Organism

基因 ID

SwissProt

Mouse
背景:

IKBKE is a noncanonical I-kappa-B (see MIM 164008) kinase (IKK) that is essential for regulating antiviral signaling pathways. IKBKE has also been identified as a breast cancer (MIM 114480) oncogene and is amplified and overexpressed in over 30% of breast carcinomas and breast cancer cell lines (Hutti et al., 2009 [PubMed 19481526]).[supplied by OMIM, Oct 2009],

细胞定位 : Cytoplasm . Nucleus. Nucleus, PML body . Targeting to PML nuclear bodies upon DNA damage is TOPORS-dependent (PubMed:20188669). Located diffusely throughout the cytoplasm but locates to punctate cytoplasmic bodies when coexpressed with TRIM6 (PubMed:24882218). .

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