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GPC1 Polyclonal Antibody

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说明书下载
货号: PG6662
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
+


靶点: GPC1
应用: WB,ELISA
反应性 : Human,Mouse,Rat
宿主物种 : Rabbit
MW(Observed): 61kD
同种型-Isotype : IgG

隐藏域元素占位

详细信息

推荐稀释比 : WB 1:500-2000;ELISA 1:5000-20000
组成 : PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal

抗原&靶点信息

特异性 : GPC1 Polyclonal Antibody detects endogenous levels of protein.
基因名称 : GPC1
蛋白名称 : Glypican-1 [Cleaved into: Secreted glypican-1]

数据库链接:

Organism

基因 ID

SwissProt

Mouse
背景:

Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. [provided by RefSeq, Jul 2008],

细胞定位 : Cell membrane; Lipid-anchor, GPI-anchor; Extracellular side. Endosome. S-nitrosylated form recycled in endosomes. Localizes to CAV1-containing vesicles close to the cell surface. Cleavage of heparan sulfate side chains takes place mainly in late endosomes. Associates with both forms of PRNP in lipid rafts. Colocalizes with APP in perinuclear compartments and with CP in intracellular compartments. Associates with fibrillar APP amyloid-beta peptides in lipid rafts in Alzheimer disease brains.; [Secreted glypican-1]: Secreted, extracellular space.

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