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货号: PK0140
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
靶点: CD41
应用: WB,IHC
反应性 : Human,Rat,Mouse,
宿主物种 : Rabbit
MW(Observed): 16kD,110kD
同种型-Isotype : IgG
隐藏域元素占位
详细信息
推荐稀释比 : WB 1:500-2000;IHC 1:50-300
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal
抗原&靶点信息
特异性 : This antibody detects endogenous levels of Human ITGA2B (light chain form 1, Cleaved-Gln891, protein was cleaved amino acid sequence between 890-891 ). It doesn't recognize light chain form 2
基因名称 : ITGA2B GP2B ITGAB
蛋白名称 : ITGA2B (light chain form 1, Cleaved-Gln891)
别名 : ITGA2B;GP2B;ITGAB;Integrin alpha-IIb;GPalpha IIb;GPIIb;Platelet membrane glycoprotein IIb;CD antigen CD41;[Cleaved into: Integrin alpha-IIb heavy chain;Integrin alpha-IIb light chain, form 1;Integrin alpha-IIb light chain, form 2]
背景:
This gene encodes a member of the integrin alpha chain family of proteins. The encoded preproprotein is proteolytically processed to generate light and heavy chains that associate through disulfide linkages to form a subunit of the alpha-IIb/beta-3 integrin cell adhesion receptor. This receptor plays a crucial role in the blood coagulation system, by mediating platelet aggregation. Mutations in this gene are associated with platelet-type bleeding disorders, which are characterized by a failure of platelet aggregation, including Glanzmann thrombasthenia. [provided by RefSeq, Jan 2016],


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