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货号: PH0847
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
靶点: CD41
应用: IHC,IF
反应性 : Human
宿主物种 : Mouse
MW(CalcμLated) : 113kD
隐藏域元素占位
详细信息
推荐稀释比 : IHC 1:100;IF 1:50-200
组成 : PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.
纯化工艺 : The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
克隆性 : Monoclonal
克隆号 : Q90
抗原&靶点信息
特异性 : The antibody detects endogenous human CD41/ Intergrin α2b protein.
基因名称 : ITGA2B
蛋白名称 : Integrin αIIb
别名 : ITGA2B;GP2B;ITGAB;Integrin alpha-IIb;GPalpha IIb;GPIIb;Platelet membrane glycoprotein IIb;CD antigen CD41;[Cleaved into: Integrin alpha-IIb heavy chain;Integrin alpha-IIb light chain, form 1;Integrin alpha-IIb light chain, form 2]
背景:
This gene encodes a member of the integrin alpha chain family of proteins. The encoded preproprotein is proteolytically processed to generate light and heavy chains that associate through disulfide linkages to form a subunit of the alpha-IIb/beta-3 integrin cell adhesion receptor. This receptor plays a crucial role in the blood coagulation system, by mediating platelet aggregation. Mutations in this gene are associated with platelet-type bleeding disorders, which are characterized by a failure of platelet aggregation, including Glanzmann thrombasthenia. [provided by RefSeq, Jan 2016],


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