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详细信息
推荐稀释比 : WB 1:1000;ICC 1:100;IF 1:50-200
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
克隆性 : Monoclonal
抗原&靶点信息
特异性 : This antibody detects endogenous levels of RBBP5 and does not cross-react with related proteins.
基因名称 : rbbp5
蛋白名称 : Retinoblastoma-binding protein 5
别名 : RBBP 5;RBBP-5;RBBP5;RBBP5_HUMAN;RBQ-3;RBQ3;Retinoblastoma binding protein 5;Retinoblastoma binding protein RBQ3;Retinoblastoma binding protein5;Retinoblastoma-binding protein 5;Retinoblastoma-binding protein RBQ-3;SWD1;SWD1, Set1c WD40 repeat protein, homolog.
背景:
This gene encodes a ubiquitously expressed nuclear protein which belongs to a highly conserved subfamily of WD-repeat proteins. The encoded protein binds directly to retinoblastoma protein, which regulates cell proliferation. It interacts preferentially with the underphosphorylated retinoblastoma protein via the E1A-binding pocket B. Three alternatively spliced transcript variants that encode different protein isoforms have been described for this gene. [provided by RefSeq, Jul 2010],


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