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货号: PS0222
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
靶点: E2F-3
应用: WB,ELISA
反应性 : Human:K168,Mouse:K160,Rat:K161
宿主物种 : Rabbit
MW(Observed): 50kD
同种型-Isotype : IgG
隐藏域元素占位
详细信息
修饰-Modification : Acetyl
推荐稀释比 : WB 1:500-10000;ELISA 1:10000
组成 : PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.
纯化工艺 : The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal
抗原&靶点信息
特异性 : This antibody detects endogenous levels of E2F-3 at Human:K168;Mouse:K160;Rat:K161, It doesn't reacte with total protein.
基因名称 : E2F3 KIAA0075
蛋白名称 : E2F transcription factor 3
别名 : E2F3 KIAA0075
背景:
This gene encodes a member of a small family of transcription factors that function through binding of DP interaction partner proteins. The encoded protein recognizes a specific sequence motif in DNA and interacts directly with the retinoblastoma protein (pRB) to regulate the expression of genes involved in the cell cycle. Altered copy number and activity of this gene have been observed in a number of human cancers. There are pseudogenes for this gene on chromosomes 2 and 17. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2013],


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