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货号: PH0780
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
靶点: IκB-α
应用: IHC,WB
反应性 : Human,Mouse,Rat
宿主物种 : Mouse
MW(Observed): 40kD
隐藏域元素占位
详细信息
推荐稀释比 : IHC1:50-200;WB 1:1000-2000
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Monoclonal
克隆号 : 2A5
抗原&靶点信息
特异性 : This antibody detects endogenous levels of IκB α at Human, Mouse,Rat
基因名称 : NFKBIA IKBA MAD3 NFKBI
蛋白名称 : NF-kappa-B inhibitor alpha
别名 : NF-kappa-B inhibitor alpha;I-kappa-B-alpha;IkB-alpha;IkappaBalpha;Major histocompatibility complex enhancer-binding protein MAD3;
背景:
This gene encodes a member of the NF-kappa-B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF-kappa-B/REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T-cell immunodeficiency autosomal dominant disease. [provided by RefSeq, Aug 2011],


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